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Image Search Results
Journal: Cardiovascular Diabetology
Article Title: The sodium–glucose co-transporter 2 inhibitor empagliflozin attenuates cardiac fibrosis and improves ventricular hemodynamics in hypertensive heart failure rats
doi: 10.1186/s12933-019-0849-6
Figure Lengend Snippet: Empagliflozin attenuates hypertension-induced collagen deposition in cardiac fibrosis of left atrial and left ventricular. Collagen fiber deposition and arrangement was demonstrated by second-harmonic generation (SHG) microscopy for left atrial ( a ) and left ventricular ( b ) tissue of normo-tensive rats (WKY), spontaneous hypertensive rats (SHR), and empagliflozin-treated SHR (EMPA). All scans are transmural and show the whole myocardial wall (from left to right: endocardium or luminal surface to epicardium or pericardium). Collagen deposition is demonstrated with high SHG intensity
Article Snippet: The authors also thank Dr. Shean-Jen Chen for providing the use of the second-harmonic
Techniques: Microscopy